19th EUFEPS Talks

We want to invite you to the 19th EUFEPS Talks on December 9, 2024 at 4 pm CET.

Marilyn N. Martinez will give a talk with the title: "Meeting The Therapeutic Challenges Facing Animal Health in the 21^st Century and its Importance to One Health".

Abstract:

Given the complexities facing medicine and the pharmaceutical sciences, information exchange between human and veterinary scientists and practitioners is essential.  Whether facing the need to identify therapeutic solutions to shared diseases, the need to utilize new and existing tools to better understand in vivo dose-exposure-response relationships, or developing in vitro approaches for predicting the bioequivalence of products that are not systemically absorbed, there is much we can learn from each other.  In this presentation, commonalities will be discussed from the perspective of addressing these complex issues. Topics will be discussed from the perspectives research being conducted within the framework of veterinary medicine.

CV:

Dr. Marilyn N. Martinez is an internationally recognized expert in veterinary pharmacokinetics.  She currently serves as a Senior Biomedical Research and Biomedical Product Assessment Service (SBRBPAS) Expert for the US Food and Drug Administration (FDA) Center for Veterinary Medicine (CVM).  As such, she is uniquely responsible for spearheading research efforts that support the development of novel approaches for evaluating veterinary dosage forms.  Her research areas include the development of in silico models to explore in vivo drug behavior in dogs (CRADA with Simcyp^TM), breed differences in GI physiology and product absorption, novel approaches for the bioequivalence evaluation of nonsystemically absorbed drugs (oral, opthalmic, and intramammary infusion), examination of potential mechanisms for evaluating antivirulence compounds intended for veterinary use, development of alternative study designs for evaluating product bioequivalence when full drug concentration/time profiles cannot be generated in a single subject (e.g., fish and other small animals), and the development of canine organoids to support the evaluation of drug permeability and metabolism as a function of location within the canine GI tract (research collaboration with UGa and 3D Health Solutions, Inc).

In addition to her scientific responsibilities at the FDA, Dr. Martinez chairs the veterinary ICH working group that is developing an international guideline for between-strength biowaivers, is a scientific advisor to the Veterinary Antimicrobial Susceptibility Testing Subcommittee of the Clinical Laboratory and Standards Institute (CLSI), chaired the Breakpoint Task Force which developed and is currently updating the CLSI guideline for incorporating exposure-effect relationships into the establishment of veterinary interpretive criteria (VET-02), and is an Associate Editor of the AAPS Journal.

Among the honors received, Marilyn was elected to AAPS Fellow in 2003, is a Fellow of the Controlled Release Society, and is a Distinguished Fellow of the American Academy of Veterinary Pharmacology and Therapeutics.

Registration:

A registration is needed for this event. Please use the following link: https://us06web.zoom.us/meeting/register/tZcvfuCoqj8sEtyAXzYIjOn8JVDhOy-U-p0X. After the registration you will receive an E-Mail with the log-in details.